Literature summary extracted from

Romanowicz, L.; Gogiel, T.; Galewska, Z.; Bruczko, M.; Baczyk, J.; Roszkowska-Jakimiec, W.; Sobolewski, K.
Divergent changes in the content and activity of MMP-26 and TIMP-4 in human umbilical cord tissues associated with preeclampsia (2018), Eur. J. Obstet. Gynecol. Reprod. Biol., 231, 48-53 .

Application

EC Number	Application	Comment	Organism
3.4.24.B7	medicine	all umbilical cord tissues, both control and preeclamptic, express MMP-26 and issue inhibitor of matrix metalloproteinase TIMP-4 in macromolecular complexes. Preeclampsia induces a significant increase in the content and actual activity of MMP-26 in umbilical cord vein and Wharton's jelly. The content of TIMP-4 in preeclamptic umbilical cord vein and Wharton's jelly is reduced. The content of MMP-26 mRNA is lower in umbilical cord arteries and veins, whereas higher in Wharton's jelly in preeclampsia	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.24.B7	Homo sapiens	Q9NRE1	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.24.B7	umbilical cord	-	Homo sapiens	-

Expression

EC Number	Organism	Comment	Expression
3.4.24.B7	Homo sapiens	preeclampsia induces a significant increase in the content and actual activity of MMP-26 in umbilical cord vein and Wharton's jelly	up

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Release 2023.1 (January 2023)